A model of cholinergic modulation in olfactory bulb and piriform cortex

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Title: 1 a Model of Cholinergic Modulation in Olfactory Bulb and Piriform Cortex 2

15 In this work we investigate in a computational model how cholinergic inputs to the 16 olfactory bulb (OB) and piriform cortex (PC) modulate odor representations. We use 17 experimental data derived from different physiological studies of ACh modulation of the 18 bulbar and cortical circuitry and the interaction between these two areas. The results 19 presented here indicate that cholinergic ...

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A model of cholinergic modulation in olfactory bulb and piriform cortex.

In this work we investigate in a computational model how cholinergic inputs to the olfactory bulb (OB) and piriform cortex (PC) modulate odor representations. We use experimental data derived from different physiological studies of ACh modulation of the bulbar and cortical circuitry and the interaction between these two areas. The results presented here indicate that cholinergic modulation in t...

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Cholinergic modulation of dopaminergic neurons in the mouse olfactory bulb.

Considerable evidence exists for an extrinsic cholinergic influence in the maturation and function of the main olfactory bulb. In this study, we addressed the muscarinic modulation of dopaminergic neurons in this structure. We used different patch-clamp techniques to characterize the diverse roles of muscarinic agonists on identified dopaminergic neurons in a transgenic animal model expressing ...

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Noradrenergic and cholinergic modulation of olfactory bulb sensory processing

Neuromodulation in sensory perception serves important functions such as regulation of signal to noise ratio, attention, and modulation of learning and memory. Neuromodulators in specific sensory areas often have highly similar cellular, but distinct behavioral effects. To address this issue, we here review the function and role of two neuromodulators, acetylcholine (Ach) and noradrenaline (NE)...

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The accessory olfactory bulb (AOB), the first relay of chemosensory information in the Vomeronasal system, receives extensive cholinergic innervation from the basal forebrain. Cholinergic modulation of neuronal activity in the olfactory bulb has been hypothesized to play an important role in olfactory processing; however, little is known about the cellular actions of acetylcholine (ACh) within ...

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2013

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.00577.2012